Mitochondria-Localized Three-Color Fluorescent Sensor for Concurrent Tracking of Mitochondrial H2O2, Hypochlorite and Subcellular Viscosity during Oxidative Stress and Drug-Related Hepatic Damage
We report a naphthalimide derived mitochondrial targeting fluorescent probe MT for real time simultaneous visualization of mitochondrial hydrogen peroxide (H2O2), hypochlorite (ClO−), and subcellular microviscosity, three key biomarkers closely associated with oxidative stress mediated drug induced liver injury. Free...