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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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Ming-Ming Zhao

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Open access Sep 2026

SYVN1-mediated succinate accumulation exacerbates heart failure.

Metabolic remodeling, defined as changes in the energy substrate preferences and energy production efficiency of the myocardium, is one of the pathogenic characteristics of failing hearts, though its molecular mechanisms remain incompletely understood. Through untargeted metabolomics coupled with targeted mass spectrom...

Hong-Tu Cui, Lu Fang, Huan-Huan Cao et al. · 0 citations
Open access Aug 2026

Myocilin drives cardiomyocyte mitochondrial dysfunction via SLC3A2-dependent redox imbalance in heart failure

Fibroblast-derived myocilin is identified as a fibroblast-derived mediator that drives cardiomyocyte mitochondrial dysfunction and ROS production in HF and a fibroblast–cardiomyocyte signaling axis in which myocilin disrupts cardiomyocyte metabolic homeostasis is identified.

Xiaoyue Yu, Junxia Zhang, Jun-Fang Wu et al. · 0 citations

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