Open access
Oct 2026
A single residue in the Gc protein dictates neutralization sensitivity and virulence in SFTSV.
Severe fever with thrombocytopenia syndrome virus (SFTSV), a World Health Organization (WHO) priority pathogen, causes hemorrhagic fever with up to 30% case fatality and lacks approved vaccines or therapeutics. Here, we isolated Gc-specific monoclonal antibodies H2, H4, and H12. H2 potently neutralized endemic Chinese...
Xiao-Yu Zhang, Xue-Kai Zhang, Pei-Pei Yang et al.
· Cell Reports · 0 citations