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Ming-Rui Chang

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Open access Oct 2026

Structure-Based Identification of Potential Toll-Like Receptor 3 Agonists for Anti-HBV Applications

Hepatitis B virus (HBV) infection remains a major global public health burden, primarily due to the persistence of covalently closed circular DNA (cccDNA) in infected hepatocytes. Toll-like receptor 3 (TLR3) has been suggested to be a promising therapeutic target, as its activation stimulates innate immune responses th...

Szu-Hung Chen, Ming-Rui Chang, Yih Ho et al. · 0 citations

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