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Author

Mingtao Feng

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Review Open access Sep 2026

Prostate-specific membrane antigen in malignant brain tumors: vascular heterogeneity, imaging promise, and therapeutic challenges

Malignant brain tumors have high morbidity and poor prognosis. Prostate-specific membrane antigen (PSMA) has emerged as a promising vascular biomarker in this setting, particularly in gliomas and brain metastases. This review synthesizes current evidence on PSMA expression patterns, regulatory mechanisms, imaging appli...

Bihani Pokharel, Ming-Tao Feng, Yue-Fei Yang et al. · 0 citations
Open access Jul 2026

Upregulation of macrophage UPP1 promotes lung adenocarcinoma metastasis through an mtROS-cGAS-NLRP3 inflammasome axis.

A macrophage-specific immunometabolic circuit in which UPP1-driven mitochondrial stress activates the mtROS-cGAS-NLRP3 axis, promoting IL-1β-dependent macrophage-tumor crosstalk and metastatic progression is identified.

Mingtao Feng, Chao Gao, Yue-fei Yang et al. · 0 citations

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