Open access
Aug 2026
Deoxycholic Acid Impairs Immune Tolerance during DC and CD4 T Cell Interaction through FXR-Dependent Signaling
Deoxycholic acid (DCA) was implicated in gut dysbiosis and inflammation, but its immunoregulatory mechanisms in allergic sensitization remain unclear. This study investigated how DCA disrupts intestinal immune tolerance, thereby promoting an immune response of lymphocytes to allergens. In vivo, the functions of int...
Jinqi Yuan, Ming-Tao Yu, Yuhui Chen et al.
· Food Science and Human Welln... · 0 citations