Ming-Wei Feng

N-Terminal Basic Helix and S120 Phosphorylation Cooperatively Regulate Nuclear Localization of UBE2A/B in Mechanotransduction

Simple Summary Cells experience physical cues from their environment, which influence gene expression through mechanotransduction. We previously found that Ubiquitin-conjugating enzyme E2 A/B (UBE2A/B) move into the nucleus under stiff or low-density conditions, promoting histone H2B (H2B) monoubiquitination and cell g...