Proximal Tubular EZH2 Inhibits Diabetic Kidney Disease by Suppressing SHC1-Mediated Oxidative Stress.
Diabetic kidney disease (DKD) represents one of the most severe complications of diabetes. Although EZH2 (Enhancer of Zeste Homolog 2) has been implicated in renal injury and diabetes, its specific function within renal tubular cells in DKD remains unclear. Here, we explored the role and downstream mechanism of tubular...