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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Ming-Xiu Xu

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Open access Sep 2026

Deubiquitinase USP8 inhibits HIV-1 replication by suppressing Tat-mediated viral transactivation

ABSTRACT Ubiquitin-specific proteases (USPs) modulate diverse virus-host interaction events through deubiquitination; thus, investigating their functional roles and molecular targets facilitates the interpretation of viral pathogenic mechanisms and informs the design of anti-virus strategies. The deubiquitinase USP8 ha...

Jin-Song Yuan, Wei-Jing Yang, Ming-Xiu Xu et al. · 0 citations

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