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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Mingyang Sheng

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Open access Oct 2026

Prediction of Lindane-Induced Breast Cancer Toxicity Through Multi-Target Network Analysis and Mechanistic Investigation

This study aimed to identify potential molecular targets associated with Lindane-induced molecular alterations in breast cancer and elucidate its toxicological mechanisms using an integrated strategy combining network toxicology, machine learning, molecular simulation, and experimental validation. Lindane-related targe...

Y. Lin, Jia-Hui Xu, Ming-Yang Sheng et al. · 0 citations
Aug 2026

Multi-Omics-Driven Network Pharmacology and Experimental Validation Reveal the Molecular Mechanism of Bupi Yichang Pill in Treating Ulcerative Colitis Through Regulation of the PI3K/Akt/IKK/NF-κB Pathway.

Multi-omics analysis revealed that BYP restored gut microbiota dysbiosis, ameliorated bile acid and amino acid metabolism, and modulated the expression of inflammation- and barrier-related genes, providing both a mechanistic basis and pharmacological rationale for its traditional clinical use in UC management.

Yunlu Zou, Zi-Zhao Yang, Jiatong Liu et al. · 1 citation

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