Author

Ming You

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Review Open access Sep 2026

In situ vaccination for the treatment of localized cancer and the prevention of metastatic disease

In situ vaccination (ISV) is a local tumor-directed immunotherapy strategy that uses a treated tumor as an endogenous, patient-specific source of tumor antigens and a site of immune activation, with the goal of converting local treatment into systemic and durable antitumor immunity. Depending on the modality, ISV induc...

Sang-Been Lee, M. Kim, Yian Wang et al. · Frontiers in Immunology · 0 citations

Review Open access Jul 2026

Targeting mitochondria for the treatment of neurodegenerative diseases

This Review summarizes mitochondrial pathological mechanisms in neurodegenerative diseases and discusses emerging mitochondria-targeted therapeutic strategies, highlighting delivery technologies, therapeutic modalities, and translational challenges.

Qian Li, Ming You · Frontiers in Neuroscience · 0 citations