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Ming-Yue Lv

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Open access Sep 2026

PROTAC probe-assisted degradomics identifies SPINT2 as a candidate cellular target involved in the anti-cancer activity of Flupentixol.

Targeted protein degradation has emerged not only as a therapeutic modality but also as a useful strategy for target deconvolution. This study investigated the anti-cancer activity and pharmacological targets of the anti-psychotic drug Flupentixol using a PROTAC probe-assisted degradomics strategy. We first verified th...

Ming-Yue Lv, Qing-Yuan Hu, Jing-Kai Liang et al. · 0 citations

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