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Author

Mingjie Ding

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Aug 2026

Isolinderalactone alleviates hepatic ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress through the SIRT1/IRE1α signaling pathway.

ILL attenuates HIRI by simultaneously elevating SIRT1 expression and activating its deacetylase function, thereby restraining IRE1α-dependent ERS and subsequent hepatic injury, highlighting ILL as a promising therapeutic candidate for the management of perioperative HIRI.

Hao Li, Zhen-Yu Guan, Wendong Li et al. · 0 citations

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