The role of Mfn2/PERK mediated ER-mitochondrial communication in autophagy induced by silica nanoparticles in HT22 cells.
Widespread application of silica nanoparticles (SiNPs) has raised concerns regarding potential neurotoxic risks, yet the complex mechanisms underlying cellular damage remain incompletely understood. Mitochondria associated endoplasmic reticulum membranes (MAMs), which are regulated by the key tethering protein Mitofusi...