Mingqiang Gong

Microglia–astrocyte crosstalk as a key organizing principle of Alzheimer’s disease: from homeostatic cooperation to maladaptive signaling loops

Alzheimer’s disease (AD) has long been framed around amyloid-beta (Aβ) and tau pathology, yet mounting evidence indicates that dysfunctional microglia–astrocyte crosstalk is an important, and often underappreciated, contributor to disease progression that operates alongside—rather than in place of—neuronal, vascular, a...