Defining the genetic landscape of acid and oxidative stress tolerance in Streptococcus mutans by pooled CRISPR interference screening
Bacterial stress tolerance is a fundamental ecological adaptation that enables survival, competitive fitness, and persistent colonization under fluctuating environmental conditions. Dental caries remains a major global health burden. As an etiologic agent in caries, Streptococcus mutans (S. mutans) has the ability to a...