Review
Open access
Jul 2026
Research progress of small molecule protein kinase inhibitors (SMKIs) in the treatment of colorectal cancer: mechanism, application, and future prospects
Future development of SMKI-based therapy in CRC will require biomarker-guided patient selection, rational combination strategies, dynamic monitoring of resistance, and prospective validation using clinically meaningful endpoints.
Lei Liu, Yingjun Chen, Ming-Xin Guo et al.
· Frontiers in Pharmacology · 0 citations