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Author

Mingyuan Zhou

2 papers indexed here

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Aug 2026

Tetrastigma hemsleyanum polysaccharides ameliorate inflammatory bowel disease via sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 -mediated gut vascular barrier repair.

BACKGROUND Inflammatory bowel disease (IBD) is a chronic, relapsing inflammatory disorder characterized by compromised intestinal barrier integrity. PURPOSE This study aimed to elucidate the therapeutic mechanisms of Tetrastigma hemsleyanum polysaccharides (THP) in restoring the gut vascular barrier (GVB) via the sph...

Wenxuan Li, Yi-Wen Hu, Menghan Yang et al. · 0 citations
Open access Jul 2026

Colon-targeting pH-responsive Bletilla striata polysaccharide coacervate microdroplets for ulcerative colitis therapy via macrophage reprogramming

Ulcerative colitis (UC) is an immune-mediated chronic inflammatory bowel disease that severely impairs patients’ quality of life. Efficient oral colon-targeted delivery systems are urgently needed to improve local therapeutic efficacy while minimizing systemic exposure. Herein, we developed a pH-responsive Eudragit S10...

Qiantao Zhang, L. Chai, Hui Liu et al. · 0 citations

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