Open access
Jul 2026
Identification of substrates of the protein tyrosine phosphatase PTP1B using in situ site-specific photo-crosslinking
The use of site-specific photo-crosslinking to covalently capture the substrates of tyrosine phosphatases in situ reveals previously unknown roles of PTP1B in signaling systems and could be readily extended to other tyrosine phosphatases in the same family.
Andrew C. Johns, Yethmie S. Goonatilleke, David C. Cabanero et al.
· bioRxiv · 0 citations