IP-10 Drives TCF1+ Stem-like CD8+ T Cell Depletion and Terminal Differentiation in Lupus Nephritis 2308427
Lupus nephritis (LN) is characterized by kidney damage due to immune dysregulation. CD8+ T cell dysfunction contributes to tissue injury, however, the mechanisms regulating CD8+ T cell fate during autoimmunity remain unclear. In particular, the effect of inflammatory chemokines on the balance between stem-like an...