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Miranda M. Lim

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Review Sep 2026

Consensus practice recommendations for management of sleep dysfunction in Parkinson disease.

INTRODUCTION Sleep disturbances are highly prevalent in people with Parkinson's disease (PD). Adhering to practical, evidence-informed guidelines enhances care delivery and quality of life in PD. Therefore, we sought to develop consensus statements on screening, diagnosis, and treatment of sleep dysfunction in PD. ME...

Carine W. Maurer, Delaram Safarpour, J. Lee-Iannotti et al. · 1 citation
Open access Aug 2026

Aquaporin-4 mis-localization decreases glymphatic clearance of α-synuclein in an alpha-syntrophin knock out mouse model and promotes α-synuclein pathology and aggregate propagation.

Results indicate α-synuclein clearance and propagation are mediated by glymphatic function and that aquaporin-4 mis-localization observed in the presence of human synucleinopathy may contribute to the development and propagation of Lewy body pathology in conditions such as Lewy body dementia and Parkinson's disease.

Molly Braun, Matthew J. Simon, Jay Jang et al. · 0 citations

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