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Author

Mireia Díaz

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Jul 2026

Agentic Calibration of Grey-Box Simulation Models: An LLM-Driven Alternative

This work introduces an agentic calibration method in which a large language model acts as the optimizer, with constraints incorporated as a plain-language section of the system prompt, and evaluates the agentic method, NM, and Bayesian Optimization on an anal cancer simulation model under both unconstrained and clinic...

David Gómez-Guillén, Mireia Díaz, J. L. Arcos et al. · 0 citations

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