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Sep 2026

Appropriate Therapy and Survival in Carbapenem-Resistant Enterobacterales Bacteremia: A Multicenter Cohort Study on Epidemiology and Risk Factors.

BACKGROUND Carbapenem-resistant Enterobacterales (CRE) bloodstream infections are associated with high mortality and limited treatment options. This study aimed to characterize CRE epidemiology, identify risk factors for 30-day mortality, and evaluate the impact of appropriate combination therapy on mortality in patien...

Yae Jee Baek, Se Yoon Park, Jung Ho Kim et al. · 0 citations
Open access Aug 2026

Berberine promotes host lipolysis to enhance antimicrobial defense against hypervirulent Klebsiella pneumoniae infection.

Hypervirulent Klebsiella pneumoniae (hvKp) is an emerging pathogen that causes severe community-acquired infections; however, the immune mechanisms controlling intracellular hvKp have yet to be clearly defined. In this study, we investigated the therapeutic potential of berberine against hvKp infection and elucidated t...

Ju Yeong Lee, Hui-Jung Jung, Anwesha Ash et al. · 0 citations

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