Open access
Sep 2026
Large-scale organoid-derived cyst cultures as a drug discovery platform for polycystic kidney disease.
INTRODUCTION Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the slow, progressive formation of fluid-filled cysts within the kidneys, ultimately leading to kidney failure. Despite being the most common genetic kidney disease, therapies for ADPKD are limited. Ureteric bud (UB) organoids derived...
T. Vanichapol, Ruby Wangford, Shyla Mishra et al.
· Kidney International · 0 citations