Miss S. H. Wei

Propranolol attenuates social isolation-associated anxiety-like behavior, immune dysfunction, and melanoma progression in mice, with involvement of β-adrenergic signaling

Social isolation stress is associated with melanoma progression and immune alterations via altered β₂-AR-mediated SOX10–PD-L1 expression while also being associated with anxiety-related behaviors; propranolol demonstrated effects on emotional regulation and antitumor immune function, providing a preclinical basis for f...