Development of HPTLC method for simultaneous estimation of Gatifloxacin and Flurbiprofen Sodium using 32 factorial design.
INTRODUCTION This study aimed to develop and validate an Analytical Quality by Design (AQbD)-based HPTLC method for simultaneous estimation of gatifloxacin and flurbiprofen sodium in ophthalmic formulations. METHODS Separation was achieved on silica gel 60 F254 precoated HPTLC plates using n-propanol: ammonia (8:2, v...