Fast and robust T1 mapping based on a 3D dual-echo UTE sequence (PETALUTE) for superparamagnetic iron oxide nanoparticle (SPION) biodistribution assessment.
BACKGROUND Superparamagnetic iron oxide nanoparticles (SPIONs), such as ferumoxytol, are promising theranostic agents that can be assessed with MRI. Relaxation time mapping can provide reproducible and quantitative biomarkers of SPION distribution, suitable for longitudinal and cross-individual studies. However, conven...