Open access
Sep 2026
Cryo-EM structures of CENP-A nucleosomes isolated from human cells
Centromeres ensure accurate chromosome segregation, and their identity is specified epigenetically by the histone H3 variant CENP-A. Although the structures of reconstituted CENP-A nucleosomes have provided important insights, how this epigenetic mark is structurally organized within native chromatin remains incomplete...
Eisho Tanida, Suguru Hatazawa, Takumi Oishi et al.
· Communications Biology · 0 citations