NPM1 drives cancer cell migration and invasion by amplifying EGFR gene expression and its downstream signaling
Mitsuru Okuwaki, Nowrin Rashid, Shoko Saito et al.
· 0 citations
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Review
Sep 2026
Target-Site Selection by Transcription Factors: Roles of DNA, Chromatin, and Cofactor-Mediated Regulation.
This review outlines how DNA/chromatin features and TF-centered mechanisms contribute to target-site selection and highlights DNA-binding domain-directed cofactor regulation as an underappreciated mechanism that modulates TF-DNA binding and may help explain selective genomic occupancy.
Mitsuru Okuwaki
· Journal of Biochemistry (Tok... · 0 citations