Mohamed Elsaid

Perioperative discovery of KLKB1 c.451dupT mutation causing prekallikrein deficiency in a Saudi child: A case report of safe surgery despite isolated severe aPTT prolongation

Prekallikrein deficiency, a rare autosomal recessive disorder, results in isolated prolongation of activated partial thromboplastin time (aPTT) without associated bleeding symptoms. This condition often complicates preoperative screenings and can lead to unnecessary testing and healthcare expenditures. We report the fi...