Review
Open access
Sep 2026
Targeting MYC-Driven Cancers: From Oncogenic Addiction to Therapeutic Vulnerability
The MYC family oncoproteins, including MYC, MYCN, and MYCL, are potent drivers of tumorigenesis across a broad range of human cancers, frequently linked to aggressive tumor behavior, poor prognosis, and therapy resistance. They function as master transcriptional regulators that orchestrate gene expression programs gove...
Lourdes Sainero-Alcolado, Dilraj Lama, M. Alzrigat et al.
· BioDrugs · 0 citations