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Author

Mohammad Hossein Mokhtari

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Open access Sep 2026

Design of a spermine-β-cyclodextrin functionalized gelatin nanoaggregate hydrogel for nose-to-brain delivery of donepezil

Rapid mucociliary clearance and limited permeability across biological barriers remain major challenges for efficient nose-to-brain delivery of donepezil (DNP). Herein, we report a rationally engineered biodegradable gelatin hydrogel in which chemically conjugated spermine-β-cyclodextrin (SPM-β-CD) nanoaggregates were...

Z. Mokhtari, S. Hashemnia, Reza Heidari et al. · 0 citations

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