Novel Azo Sulfonamide Derivatives of 5-Sulfosalicylic Acid: Synthesis, Biological Evaluation, and Computational Profiling
The escalating crisis of multi-drug-resistant pathogens necessitates the development of novel therapeutic scaffolds with enhanced membrane permeability and multi-target inhibitory potential. This study describes the design, synthesis, and mechanistic evaluation of five novel azo-sulfonamide hybrids (4a–e) derived from...