Open access
Oct 2026
Design and Synthesis of Novel Biginelli Adducts: Anticancer Activity and In Silico Study
ABSTRACT In this study, we report the synthesis of 14 Biginelli adducts and the evaluation of their anticancer activity against three human cancer cell lines: MCF‐7 (breast), SW480 (colon), and Hep‐G2 (liver), as well as the noncancerous Hek‐293 cell line. Among the synthesized derivatives, compound 8n emerged as the m...
Aida Iraji, Sara M. Farid, Mohammadreza Eftekharian et al.
· Chemistry and Biodiversity · 0 citations