Open access
Jul 2026
Transcription initiation drives dosage compensation establishment and maintenance in male Drosophila
Dosage compensation (DC) in Drosophila equalizes X chromosome–linked gene expression via the male-specific lethal complex, which acetylates histone 4 lysine-16 on the male X chromosome. How DC is established during early embryogenesis remains obscure, largely due to the difficulty of obtaining sufficient sex-specific m...
Ronald Oellers, A. Alexiadis, Yidan Sun et al.
· Science Advances · 0 citations