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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Monica M. Sousa

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Open access Sep 2026

Distinct Arp2/3 isocomplexes drive axonal actin ring assembly and integrity

The actin-related protein 2/3 (Arp2/3) complex is a central nucleator of branched actin filaments, essential for numerous cellular processes. Using superresolution imaging, we demonstrate that Arp2/3 is a component of the membrane periodic skeleton (MPS)—a highly ordered actin ring-spectrin lattice in the submembrane a...

A. R. Costa, Teresa Lopes, Luís P. Rodrigues et al. · 0 citations
Open access Sep 2026

In vitro programming and pseudounipolarization of human iPSC-derived sensory neurons

Ectopic expression of NGN1, BRN3A and ISLET1 (NBI) from a safe harbor locus in induced pluripotent stem cells (iPSCs) yielded robust differentiation into functional sensory neurons (iNBI-SNs) within seven days. Single nucleus transcriptomics identified peripheral sensory neuron profiles of nociceptors and mechanorecept...

Pascal Röderer, A. C. Costa, M. Lürkens et al. · 0 citations
Review Open access Jul 2026

Curving Actin Across Systems: Do Axonal Actin Rings Share Common Underlying Mechanisms?

Actin polymerization into curved and ring‐shaped structures is an evolutionarily conserved mechanism that cells use to generate force, transmit tension, and maintain membrane architecture. In neurons, super‐resolution imaging has revealed a striking periodic submembranous scaffold in axons, composed of circumferential...

A. R. Costa, Luís P. Rodrigues, Monica M. Sousa · 0 citations

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