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Monika Dede

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Open access Sep 2026

Association of tirzepatide with reverse cardiac remodeling and improved diastolic function in obesity-related HFpEF: A prospective real-world cohort study.

BACKGROUND Obesity-related heart failure with preserved ejection fraction (HFpEF) is characterized by concentric remodeling, diastolic dysfunction, and systemic inflammation. Tirzepatide, a dual GIP/GLP-1 receptor agonist, produces substantial weight loss, but real-world echocardiographic evidence of cardiac reverse re...

J. Karanxha, Mirjeta Guni, N. Xhabija et al. · 0 citations

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