Monika Gensicka-Kowalewska

Synthesis, Structure-Activity Studies, and Therapeutic Potential of Met-enkephalin Derivatives.

One potential drug with analgesic, anticancer, and immune-enhancing properties is the endogenous pentapeptide M-ENK (opioid growth factor, OGF). A significant problem limiting its therapeutic application is its low bioavailability and short half-life in human plasma. Therefore, new analogues, as well as suitable delive...