Background Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is frequently associated with gastrointestinal manifestations; however, intestinal immune responses following SARS-CoV-2 infection remain incompletely understood. This study aimed to characterize eosi...
Shun Tamaki, Rei Kawashima, Takayuki Uematsu et al.· PLoS ONE· 0 citations
Highlights HSP47 translocates from the endoplasmic reticulum to mitochondria, serving as an essential factor for both cellular and viral protein transportation. This study reveals that HSP47-bound, mitochondria-targeted proteins induce DNA damage, ROS generation, and specific signaling pathways, highlighting their pote...
S. Surinkaew, N. Hosoya, Hiromu Ito et al.· Cells· 0 citations
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