Biophysics and Physicobiology
Tohru Minamino, Motoshi Sakai, M. Kinoshita et al.
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Open access
Sep 2026
Structural basis for substrate specificity switching revealed by the FlhA(A489E) suppressor mutation
The flagellar type III secretion system (fT3SS) switches its substrate specificity from hook-type to filament-type upon completion of hook assembly. This process is regulated by the coordinated actions of FliK, FlhB, and FlhA, but the structural mechanism underlying substrate specificity switching remains unclear. Here...
Motoshi Sakai, M. Kinoshita, N. Takekawa et al.
· Biophysics and Physicobiolog... · 0 citations