Open access
Aug 2026
GATA3-extension mutants rewire lineage identity in luminal breast cancer
It is shown that eGATA3 is associated with poor clinical outcome and remodels the luminal transcriptional program, leading to attenuation of estrogen-responsive transcription and progressive loss of luminal differentiation.
Nivedhya Venas, Mrunal Ratnaparkhi, Kartik Majila et al.
· bioRxiv · 0 citations