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Open access Sep 2026

A fungal-derived benzothiazole derivative overcomes osimertinib resistance in NSCLC by targeting SCD1

6-(2-hydroxyethyl) benzo[d]thiazol-4-ol (HBT) is identified as a promising therapeutic candidate for overcoming osimertinib resistance in NSCLC and SCD1 is suggested as a potential target for combating such resistance.

Bo-Yin Li, Yuan-Yu Ke, Jin-Hua Zhu et al. · 0 citations

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