Muattaz Hussain

Protein expression kinetics of mRNA, saRNA, and pDNA as individual or co-delivered payloads using a common lipid nanoparticle formulation.

Lipid nanoparticles (LNPs) are clinically established carriers for nucleic acid therapeutics, most notably messenger RNA (mRNA). Beyond mRNA, LNPs can be used to deliver alternative gene-expressing nucleic acids with distinct biological properties, offering opportunities to modulate expression kinetics. Here, we compar...