Muhammad A. Shohayeb

Selective Radioprotection of Normal Cells by C60-ser via the Nrf2 Antioxidant Pathway

Radiation-induced damage to normal tissues remains a major dose-limiting challenge in radiation oncology. [60]Fullerene (C60) is a potent antioxidant with the potential to reduce postradiotherapy normal tissue toxicity. Here, we demonstrate that a highly water-soluble C60 derivative, C60-ser, selectively protects nor...

Pre-treatment machine learning prediction of local failure and time to local failure after Gamma Knife radiosurgery for radioresistant brain metastases