Author

Muhammad Alaa Eldeen

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Review Open access Sep 2026

The gut microbiome-immune-antioxidant axis: Redox-driven host-microbial crosstalk as a determinant of cancer immunotherapy response

The gut microbiome, immune, and antioxidant (GIA) axis is introduced as a unifying, systems-level conceptual framework to explain treatment heterogeneity and optimize cancer immunotherapy outcomes to overcome therapeutic resistance and transition host-microbiome-immune integration from conceptual promise to clinical re...

Muhammad Alaa Eldeen, Jinwon Choi, Hyo Jeong Kim et al. · Eurasian Journal of Medicine... · 0 citations

Jul 2026

Pan-Cancer Multi-Omics and Structure-Guided Drug Discovery Identify TUBG1 as a Clinically and Immunologically Relevant Target

This pan-cancer study supports TUBG1 as a clinically and immunogenomically relevant candidate and nominates computationally prioritized inhibitors for experimental validation.

Muhammad Alaa Eldeen, E. Fayad, Soha Y Alkhaldi et al. · Journal of Computational Bio... · 0 citations