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Author

Muhammad Hassan Butt

1 paper indexed here

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Sep 2026

Balancing Precursor Supply and Enhancing Enzyme Solubility for Efficient Production of ( S )-Reticuline in Escherichia coli

Benzylisoquinoline alkaloids (BIAs) are pharmacologically valuable natural products, yet their microbial production in Escherichia coli is hindered by two major bottlenecks: (1) imbalanced metabolic flux between the two upstream precursors, 3,4-dihydroxyphenylacetaldehyde (3,4-DHPAA) and dopamine, and (2) poor solubl...

Xia-Xia Zhang, Muhammad Hassan Butt, Wen Zhang et al. · 0 citations

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