Muhammad Tasnimul Hasan

Beyond Mueller–Hinton Broth: A Scoping Review of Metabolic Context, Conditional Antibiotic Susceptibility, and Metabolism-Aware Antimicrobial Susceptibility Testing

Background. Standard antimicrobial susceptibility testing (AST) in Mueller–Hinton broth samples a single metabolic state, yet bacterial susceptibility in vivo depends on nutrient availability, host-derived metabolites, and spatial structure. The extent to which this mismatch produces clinically relevant errors in susce...