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Muyun Wu

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Open access Aug 2026

Myeloma-derived exosomal circ_0002724 promotes osteoclastogenesis through a miR-4753-3p/IFIT1 and RANK axis in myeloma bone disease

Background Myeloma bone disease (MBD) is driven by excessive osteoclast activation and progressive bone destruction, but the role of exosomal circular RNAs (circRNAs) from myeloma cells remains unclear. Methods Exosomes from U266 and MM1S cells were isolated and used to treat THP-1 cells. Osteoclast differentiation was...

N. Yi, Muyun Wu, Xiao-Jie Ma et al. · 0 citations

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