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Catalyst-Free Dynamic Crosslinking of Polydicyclopentadiene via Thiol–Ene/Imine Chemistry
The permanently crosslinked nature of thermosets fundamentally prevents recycling, creating persistent waste and environmental challenges. Among high-performance thermosets, polydicyclopentadiene (pDCPD) is widely used in transportation and infrastructure, yet most end-of-life material is landfilled or incinerated be...
Aβ42-Driven α-synuclein Fibril Polymorphism and Distinct Intracellular Aggregation
Heterotypic interactions with Aβ42 reshape α-syn aggregation pathways and fibril conformations, generating structurally distinct α-syn fibril populations with different neuronal seeding activities, which provide a molecular framework for understanding how cross-talk between amyloidogenic proteins may contribute to stru...