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N. A. Segal

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Open access Sep 2026

Evaluating the C-Score from Weight-Bearing CT as a Quantitative Imaging Biomarker for Worsening Knee Osteoarthritis Structure and Pain in the Multicenter Osteoarthritis Study.

OBJECTIVE Investigate a novel "C-score" metric of femoral bone shape, derived from weight-bearing-CT (WBCT), as an imaging biomarker for knee osteoarthritis (OA) structural progression and pain worsening in men and women with, and at increased risk for, symptomatic knee OA. DESIGN Images were acquired for 649 knees (...

S. Li, N. A. Segal, I. Tolstykh et al. · 0 citations

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